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Valuation of PD Drug Candidate

| Overview |

Our client, a clinical-stage biopharmaceutical company, sought an independent valuation for its lead drug candidate, currently in Phase II clinical trials, aimed at treating Parkinson’s Disease (PD). This evaluation was crucial to support strategic decision-making, attract potential investments, and forge critical partnerships.




CNS Disease


Asset Valuation

Transaction Value







Valuation of a Novel PD Drug Candidate

Our client is poised to introduce a groundbreaking therapeutic option in the PD treatment landscape, primarily dominated by symptomatic treatments. Their drug candidate, developed as a small molecule inhibitor, targets a novel pathway associated with neuroprotection. The challenge involved two key assessments: Firstly, evaluating the potential market adoption and value of this innovative approach amidst existing treatments. Secondly, analyzing the competitive pipeline, particularly considering the drug's disease-modifying potential in a market that is shifting towards targeted therapies.


Comprehensive Valuation and Thorough Analysis

Using the risk-adjusted Net Present Value (rNPV) methodology, the valuation considered the clinical and market entry risks intrinsic to PD drug development. The analysis incorporated an extensive market study to delineate the competitive dynamics, forecast the evolution of PD therapies, and estimate potential market expansion, which is anticipated to reach $6.0 billion by 2028. Revenue projections were made based on anticipated pricing, expected market share, and penetration rates after market launch.

Sensitivity analyses were performed on critical factors like the discount rate and expected market share to assess potential valuation impacts under various scenarios. The financial modeling included a phase-by-phase success probability adjustment to reflect the high-risk, high-reward nature of PD drug development.


Nodes Valuation Services

At Nodes, we specialize in the valuation of biotech assets, combining in-depth scientific understanding with precise financial analytics. Leveraging years of industry experience, we accurately assess the potential value of biotech innovations. Our tailored approach offers specific, actionable insights that empower strategic decision-making for our clients.

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